The global market for organ on a chip was valued at nearly $30
million in 2017. The small size of the market is mainly because the organ-on-chip
market has not yet been fully commercialized. Companies in the market are still
in the research and development phase, and organs on chips are being used by a
limited number of end-users. However, the organ on chip market is expected to
grow at a compound annual growth rate (CAGR) of an astonishing 70% to reach more
than $300 million by 2021.
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The organs on chips market is segmented into the following
segments- Lung-On-Chip, Heart-On-Chip, Liver-On-Chip, Intestine-On-Chip, Kidney-On-Chip,
Skin-On-Chip, Blood-Brain-Barrier-On-Chip, and Other Organ Models, out of which
more than 50% of the global organ on a chip market is currently contributed by
organ models for lung, kidney, intestine, heart and liver. The emphasis on
lungs-on-chips, hearts-on-chips and livers-on-chips reflects the pharmaceutical
companies spend on drug development in these areas.
Organ on a chip technology offers tremendous potential for
predicting side effects and efficacy and potentially hugely decreasing the cost
of drug testing. Microarray market and lab-on-a-chip market is the leading
trend changer for the biochip market.
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The lung-on-chip segment is one of the most commercially
used organ models. It constituted 20% of the global organ on chip market in
2017. Lung-on-chip is mainly used to study airway closure and opening, lung
inflammation, airway protein synthesis or pulmonary absorption. This segment
was followed by heart-on-chip, which constituted about 12% of the global organ
on chip market in 2017. The heart-on-chip model is used for measuring the
stresses, electrophysiology and cellular architecture of the heart.
Pharmaceutical companies are primarily using organ on a chip
in drug development process, to understand how drugs are processed by humans
and compare human models with animal models.
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